Emergence of highly connected, non-redundant micro-RNAs in breast cancer transcriptional networks and their role in the control of biological functions
Breast cancer is one of the leading causes of death for women worldwide. Alterations to the gene regulatory programs lead to perturbed gene expression patterns that in turn generate major deregulations in cellular processes in the cancer phenotype. Among the many mechanisms of gene regulation described, micro-RNA regulation is widely understood to have an important role in the onset and development of breast cancer. Identifying the functional implications of micro-RNA regulation may lead to new strategies for the treatment of this disease.